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Kala-azar: 5 symptoms of the deadly disease

04:45 PM
Kala-azar: 5 symptoms of the deadly disease
Sandfly. PHOTO/Drug Today

Mid this month, Kenya announced an outbreak of Kala-azar disease in Wajir County, leaving 18 dead and infecting more than 500 people in the last three months. 

Kala-azar, also known as visceral leishmaniasis, is a potentially fatal disease caused by Leishmania parasites, transmitted by female sandflies, and characterized by fever, weight loss, and spleen and liver enlargement. 

532 cases have been reported so far, with most patients recovering after treatment.

“We are dealing with an endemic disease, but this outbreak is severe. We urge residents to seek medical attention immediately to avoid further fatalities,” Dr Ali, a Wajir County Referral Hospital paediatrician said. 

Symptoms

The World Health Organisation (WHO) says leishmaniasis is caused by a protozoa parasite from over 20 Leishmania species. Over 90 sandfly species are known to transmit Leishmania parasites.

There are 3 main forms of the disease:-

Visceral leishmaniasis (VL), also known as kala-azar, is fatal if left untreated in over 95% of cases. It is characterized by irregular bouts of fever, weight loss, enlargement of the spleen and liver, and anaemia. Most cases occur in Brazil, east Africa and India. An estimated 50 000 to 90 000 new cases of VL occur worldwide annually, with only 25–45% reported to WHO. It has outbreak and mortality potential. 

Cutaneous leishmaniasis (CL) is the most common form and causes skin lesions, mainly ulcers, on exposed parts of the body. These can leave life-long scars and cause serious disability or stigma. About 95% of CL cases occur in the Americas, the Mediterranean basin, the Middle East and central Asia. It is estimated that 600 000 to 1 million new cases occur worldwide annually but only around 200 000 are reported to WHO.

Mucocutaneous leishmaniasis leads to partial or total destruction of mucous membranes of the nose, mouth and throat. Over 90% of mucocutaneous leishmaniasis cases occur in Bolivia (the Plurinational State of), Brazil, Ethiopia and Peru.

Leishmania parasites are transmitted through the bites of infected female phlebotomine sandflies, which feed on blood to produce eggs. Some 70 animal species, including humans, can be the source of Leishmania parasites.

Author

Francis Muli

Francis Muli is a passionate digital journalist with over seven years of experience in crafting compelling stories across various platforms. His major focus is in business, politics and current affairs. He brings a keen eye for detail and a commitment to uncovering the truth. He has contributed to leading publications across the country. When not chasing stories, you can find Muli exploring new technologies, attending local events, or reading fiction. Connect with Francis Muli on X @FMuliKE and Facebook (Francis Muli) to follow his latest stories and insights.

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